What is it?

Aspirin Exacerbated Respiratory Disease (AERD), also known as Samter's Triad or Aspirin-Exacerbated Respiratory Tract Disease (AERD), is a condition characterized by the combination of asthma, nasal polyps, and respiratory reactions to non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin.

267 Alikes with Aspirin Exacerbated Respiratory Disease

Learn from others
who are experiencing
Aspirin Exacerbated Respiratory Disease.

Additional names

This group contains additional names:
- Samter's Triad
- Aspirin-Exacerbated Respiratory Tract Disease

Signs & symptoms

- Asthma: Persistent cough, wheezing, shortness of breath, chest tightness, and respiratory distress.
- Nasal polyps: Noncancerous growths in the nasal passages that can cause congestion, runny nose, postnasal drip, and reduced sense of smell.
- Aspirin/NSAID sensitivity: Taking aspirin or NSAIDs can trigger respiratory symptoms such as asthma attacks, nasal congestion, and nasal polyp inflammation.


- Medical history: The doctor will ask about your symptoms, including any respiratory reactions to aspirin or NSAIDs.
- Physical examination: The doctor may check for nasal polyps or signs of asthma.
- Aspirin challenge: This is a controlled test where a small dose of aspirin is given under medical supervision to monitor for any adverse reactions.
- Other tests: Lung function tests, allergy testing, and imaging studies may be performed to evaluate the severity and extent of the disease.


- Medications: AERD is typically managed with a combination of medications, including:
- Corticosteroids: Nasal sprays or oral medications to reduce nasal polyps and inflammation.
- Leukotriene modifiers: Medications that help alleviate asthma symptoms and reduce nasal polyp formation.
- Mast cell stabilizers: Nasal sprays or eye drops that help prevent allergic reactions.
- Aspirin desensitization: Under medical supervision, a process of gradually increasing doses of aspirin is administered to increase tolerance and reduce reactions.
- Surgical intervention: In severe cases, where medical treatment is insufficient, surgery may be necessary to remove nasal polyps.
- Allergy management: Avoidance of aspirin and NSAIDs is recommended, and management of other allergies may help improve symptoms.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

Learn more about our editorial process for content accuracy.

Alike Wisdom

Instantly get answers to medical questions with our AI, built from the collective wisdom of our community facing similar experiences

Thank you! Your submission has been received!

Find people who are
experiencing a similar
medical reality

100% Free