What is it?

Pyridoxine deficiency refers to the body's low levels of pyridoxine, or vitamin B6. Vitamin B6 is a water-soluble vitamin found naturally in many food sources and can be added to foods and supplements. It is essential for normal brain development and keeping the nervous and immune systems healthy.

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Additional names

This group contains additional names:
- Vitamin B6 deficiency

Signs & symptoms

Individuals with borderline vitamin B6 concentrations or mild deficiency might have no signs or symptoms for months or even years. Those with prolonged or severe pyridoxine deficiency may experience peripheral neuropathy and a pellagra-like syndrome. Individuals with pyridoxine deficiency may often experience skin conditions, such as seborrheic dermatitis, which is characterized by a red, itchy rash on the scalp, face, neck and upper chest. It typically has an oily, flaky appearance and may cause swelling or white patches.


Pyridoxine deficiency can be diagnosed by clinical evaluation and physical examination. Critical signs of deficiency include dermatological findings, presence of altered mental status, and peripheral neuropathy may indicate the condition.


In vitamin B6-deficient states and illnesses, treatment dosage is variable and depends on the severity of symptoms. The vitamin is available therapeutically in both oral and parenteral formulations.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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