Understanding Pyridoxine deficiency: Causes, Symptoms, and Management

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Pyridoxine deficiency

by Alike Medical Team ∙ Updated on June 13, 2023

Additional names

This group contains additional names: - Vitamin B6 deficiency

General

Pyridoxine deficiency refers to the body's low levels of pyridoxine, or vitamin B6. Vitamin B6 is a water-soluble vitamin found naturally in many food sources and can be added to foods and supplements. It is essential for normal brain development and keeping the nervous and immune systems healthy.

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Signs & symptoms

Individuals with borderline vitamin B6 concentrations or mild deficiency might have no signs or symptoms for months or even years. Those with prolonged or severe pyridoxine deficiency may experience peripheral neuropathy and a pellagra-like syndrome. Individuals with pyridoxine deficiency may often experience skin conditions, such as seborrheic dermatitis, which is characterized by a red, itchy rash on the scalp, face, neck and upper chest. It typically has an oily, flaky appearance and may cause swelling or white patches.

Diagnosis

Pyridoxine deficiency can be diagnosed by clinical evaluation and physical examination. Critical signs of deficiency include dermatological findings, presence of altered mental status, and peripheral neuropathy may indicate the condition.

Treatment

In vitamin B6-deficient states and illnesses, treatment dosage is variable and depends on the severity of symptoms. The vitamin is available therapeutically in both oral and parenteral formulations.

Note

☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.

National Institutes of Health ∙ World Health Organization ∙ MedlinePluse ∙ Centers for Disease Control and Prevention

☝ All information has been reviewed by certified physicians from Alike

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