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Lymphocytosis

by Alike Medical Team ∙ Updated on June 13, 2023

General

Lymphocytosis, or a high lymphocyte count, is an increase in white blood cells called lymphocytes. Lymphocytes help fight off diseases, so it's normal to see a temporary increase after infection. The exact thresholds for lymphocytosis can vary slightly from one lab to another.

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Signs & symptoms

Lymphocytosis doesn’t cause symptoms. However, symptoms might be connected to the cause of the spike in white blood cell count. Depending on the cause, symptoms may range from no signs to severe. Often, people learn of a high lymphocyte count incidentally after taking a blood test to check for other conditions.

Diagnosis

A blood test called a complete blood count (CBC) with differential usually diagnoses lymphocytosis. This test shows if there is a higher-than-normal amount of lymphocytes. Another flow cytometry test might check if the lymphocytes are clonal (seen in cancers like chronic lymphocytic leukemia). Testing may also include a bone marrow biopsy to help determine the root cause of lymphocytosis.

Treatment

Lymphocytosis treatment involves resolving what is causing the high lymphocyte count. Receiving treatment for the underlying cause can help restore lymphocyte levels to normal.

Note

☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.

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