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Undifferentiated Connective Tissue Disease
Undifferentiated Connective Tissue Disease
by Alike Medical Team ∙ Updated on June 13, 2023
Additional names
This group contains additional names: - UCTD
General
Undifferentiated Connective Tissue Disease is a condition that is characterized by the presence of symptoms and laboratory features that suggest an autoimmune connective tissue disorder but do not meet the diagnostic criteria for a specific connective tissue disease such as lupus, scleroderma, or rheumatoid arthritis.
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Learn from others who are experiencing Undifferentiated Connective Tissue Disease.
Signs & symptoms
The symptoms of UCTD are varied and may include: * Fatigue * Joint pain and stiffness * Raynaud's phenomenon (fingers turning white or blue in response to cold or stress) * Skin rashes * Muscle weakness * Shortness of breath * Dry eyes and mouth * Swollen glands
Diagnosis
Diagnosis of UCTD is based on a combination of clinical symptoms, laboratory tests, and exclusion of other connective tissue diseases. Some of the laboratory tests that may be used to diagnose UCTD include: * Antinuclear Antibody (ANA) test * Anti-Ro/La Antibody test * Rheumatoid factor (RF) test * Complete Blood Count (CBC) * Erythrocyte Sedimentation Rate (ESR) * C-reactive protein (CRP) test
Treatment
The treatment of UCTD is aimed at controlling the symptoms and preventing complications. Treatment may include: * Nonsteroidal anti-inflammatory drugs (NSAIDs) for joint pain and stiffness. * Corticosteroids such as prednisone for more severe symptoms such as muscle weakness or inflammation. * Hydroxychloroquine, an anti-malarial drug, is often used to treat skin rashes and joint pain. * Immunosuppressive drugs such as methotrexate may be used to suppress the immune system in severe cases. * Monitoring for complications such as lung or heart involvement, which may require additional treatment.
Note
☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.
National Institutes of Health ∙ World Health Organization ∙ MedlinePluse ∙ Centers for Disease Control and Prevention
☝ All information has been reviewed by certified physicians from Alike
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