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Toxic epidermal necrolysis

by Alike Medical Team ∙ Updated on June 13, 2023

Additional names

This group contains additional names: - TEN

General

Toxic epidermal necrolysis is a life-threatening skin disorder characterized by blistering and peeling. Drug reactions, such as antibiotics or anticonvulsants, can cause this disorder.

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Signs & symptoms

The skin peels in sheets as a result of toxic epidermal necrolysis. Fluids and salts ooze from raw, damaged areas due to the loss of skin. It is easy for these areas to become infected. Symptoms of toxic epidermal necrolysis may be similar to those of other skin conditions. It is a life-threatening condition. Talk with your healthcare provider for a diagnosis if you are suspicious.

Diagnosis

In order to diagnose you, your doctor will ask about the drugs you have been taking and examine your body and skin.

Treatment

In most cases, the disease progresses within three days. Hospitalization, often in a burn unit, is usually part of the treatment. The medicine is discontinued if it causes a skin reaction. Fluids and electrolytes administered intravenously (IV) Treatment with antibiotics Immunoglobulin G infused intravenously

Note

☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.

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