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Systemic mastocytosis
Systemic mastocytosis
by Alike Medical Team ∙ Updated on June 13, 2023
General
Systemic mastocytosis refers to a rare condition which is characterized by accumulation of mast cells in body organs such as the skin, digestive tract and bone marrow. Mast cells may get triggered by alcohol, spicy food, insect bites, medications and release substances that cause a reaction similar to an allergic reaction. There are several types of mastocytosis.
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Learn from others who are experiencing Systemic mastocytosis.
Signs & symptoms
Symptoms depend on the site of mast cell accumulation and may include flushing, itching, hves, abdominal pain, nausea, vomiting, bleeding disorders, anemia, muscle pain, bone pain, and mood disorders.
Diagnosis
Diagnosis is based upon findings from medical history and physical examination. Further evaluation may include blood tests, urine tests, skin biopsy, imaging tests, biopsy, and genetic testing.
Treatment
Treatment depends on the type of systemic mastocytosis and the organs affected. Treatment may include avoiding triggers, medications such as antihistamines, steroids, KIT inhibitors, chemotherapy, and stem cell transplant.
Note
☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.
National Institutes of Health ∙ World Health Organization ∙ MedlinePluse ∙ Centers for Disease Control and Prevention
☝ All information has been reviewed by certified physicians from Alike
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