What is it?

Pseudocholinesterase deficiency is a rare condition, which could be genetic or acquired, characterized by increased sensitivity to muscle relaxants substances given in anesthesia. Most people with this disorder will not know of its existence until they will get exposed to the muscle relaxants succinylcholine or mivacurium.

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Additional names

This group contains additional names:
- Pseudocholinesterase deficiency

Signs & symptoms

Pseudocholinesterase deficiency makes the muscles relax for a few hours after receiving succinylcholine or mivacurium.


Pseudocholinesterase deficiency may be suspected if someone has a hard time recovering from anesthesia. Diagnosis could be done by a blood test to measure pseudocholinesterase enzyme activity. If it’s a genetic condition, genetic testing may be done.


There is no treatment but to avoid getting these certain medications.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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