What is it?

Pure red cell aplasia (PRCA) is a rare blood disorder. It happens when your bone marrow doesn’t produce the normal number of red blood cells. PRCA may be inherited or devleoped as a consequence of an other underlying disease.

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Pure Red Cell Aplasia (PRCA).

Signs & symptoms

PRCA may cause common anemia symptoms, such as:

- Tiredness.
- Difficulty breathing.
- Dizziness.
- Pale skin.
- Headaches.
- Palpitations (feeling of your own heartbeat)


To diagnose PRCA your healthcare provider will ask you about your medical history, perform a physical examination, and will refer you to blood and imaging tests:
- Complete blood count (CBC)
- Peripheral blood smear.
- Parvovirus B19 test.
- Computed tomography (CT) scan.
- Bone marrow aspiration or biopsy.


Treatment varies based on what caused you to develop PRCA. Treatment options include:
- Immunosuppressants - medications to control your immune system
- Blood transfusion - to raise your hemoglobin levels and treat your anemia
- Surgery - if an underlying disease such as tumor exists, surgeons may remove your thymus to prevent the tumor from spreading.
- Stem cell transplant - people who suffer from Diamond-Blackfan anemia may need stem cell transplants.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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