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Postcholecystectomy syndrome

by Alike Medical Team ∙ Updated on June 13, 2023

General

Postcholecystectomy syndrome refers to abdominal symptoms present after a surgery to remove the gallbladder. These symptoms may be either transient, persistent or lifelong. Most commonly, it is caused actually by extrabiliary disorders, such as pancreatitis and its complications. Biliary causes may include bile salt induced diarrhea, retained calculi, bile leak, biliary strictures and dyskinesia of the sphincter of Oddi. There could also be psychiatric and neurologic disorders that explain the symptoms.

12 people with Postcholecystectomy syndrome

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Signs & symptoms

Symptoms may include dyspepsia, fatty food intolerance, jaundice, nausea, vomiting, flatulence, bloating, diarrhea, and persistent pain in the right upper quadrant.

Diagnosis

Diagnosis of postcholecystectomy syndrome is made when there is a history of a cholecystectomy and the presence of abdominal symptoms. Other results may include ultrasound, blood tests, cholangiography, and endoscopic retrograde cholangiopancreatography (ERCP) .

Treatment

It is usually recommended to restrict fat in the diet. Sometimes, supplements such as enzyme preparations, antispasmodics, and sometimes cholagogue which promotes discharge of bile from the system. Treatment depends on the underlying cause for the symptoms buy may also include ursodeoxycholic acid for bile microlithiasis, bile acid sequestrant therapy for bile acid diarrhea

Note

☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.

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