What is it?

Panhypopituitarism is a condition in which all of the hormones which are normally secreted from the anterior pituitary gland are reduced. The pituitary gland, located in the brain, usually secretes hormones that regulate many body functions such as growth, sexual development, metabolism, water balance and response to stress. In the case of panhypopituitarism, all these functions are disrupted. Causes for panhypopituitarism include pituitary gland tumor, cysts, trauma, injury, autoimmune reaction, radiation treatment, pressure due to hydrocephalus and surgery.

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Signs & symptoms

Symptoms of panhypopituitarism may include abnormal growth and delayed puberty in children and adolescents, excessive thirst and urination, hypomenorrhea, low blood sugar, sensitivity to cold, weight loss or gain, dry skin, nausea, vomiting, dizziness, fatigue and drowsiness.


Diagnosis of panhypopituitarism is based upon findings from medical history and physical examination as well as blood and urine tests to chest hormone levels and brain imaging such as CT or MRI scans.


Treatment for panhypopituitarism depends on its cause, and may include hormone replacement therapy, surgery, and radiation therapy.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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