What is it?

Osteitis deformans (also known as Paget’s disease of bone), is a condition involving changes in the bone cells such as excessive bone breakdown and cellular disorganization.These changes cause the bone to be fragile, resulting in deformities in more than one bone. It is more common in the pelvis, tibia,femur, lumbar vertebrae and skull. The cause for Paget’s is not yet known, but it is probably a combination of genetic and acquired (viral infections) factors. Rarely, Paget’s can transform into a malignant bone disease. It is rare in people under the age of 55. Men are more affected than women.