What is it?

Necrosis of the liver, acute or subacute, refers to the process in which viable cells become nonviable. Necrosis is sometimes the result of tissue injury. Necrosis is found in acute liver failure, which means that the loss of liver function occurs over days or weeks.It is typically caused due to drug use or viral hepatitis. Necrosis can also be found in chronic liver failure, which means that the liver dysfunction occurs over months or more. Liver necrosis may change in its extent.

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Necrosis of Liver/Acute Hepatic Failure.

Additional names

This group contains additional names:
- Hepatic necrosis
- Toxic liver disease w hepatic necrosis
- Toxic liver disease with hepatic necrosis
- Yellow atrophy of liver
- Necrosis of liver
- Liver failure

Signs & symptoms

Symptoms depend on the underlying cause but may include jaundice, abdominal swelling, vomiting, nausea, bleeding, malaise, confusion, sleepiness and tremors.


Liver necrosis can be diagnosed in a liver biopsy that states the extent of injury as well as the histological grade and the degree of inflammation.


Liver necrosis is only the histological outcome of an underlying disease or condition causing liver damage- and that condition should be treated with medications, blood transfusion, nutritional support and more. Liver transplant is suggested when the liver failure cannot be reversed.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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