Myeloproliferative disorder
What is it?
Myeloproliferative disorders are a group of disorders that affect hematopoietic stem cell disorders that share a common mutation in a factor that activates JAK2, a factor that stimulates the production of blood cells. This results in the overproduction of blood cells. The most common myeloproliferative disorder is polycythemia vera. These conditions may lead to acute leukemia.
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Signs & symptoms
Symptoms may include shortness of breath, weakness, pale skin, loss of appetite, fever, weight loss, bone pain, bleeding, and purpura.
Diagnosis
Diagnosis is based upon findings from medical history and physical examination. Further evaluation may include blood tests and bone marrow biopsy.
Treatment
Treatment depends on the exact disorder and may include watchful waiting,chemotherapy, radiation therapy, phlebotomy, gene therapy, hormone therapy, stem cell transplant, or a surgery to remove the spleen.
☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.
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