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Mayer-Rokitansky-Kuster-Hauser syndrome

by Alike Medical Team ∙ Updated on June 13, 2023

Additional names

This group contains additional names: - MRKH

General

Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a congenital condition in which the female reproductive system does not develop properly. Women with MRKH syndrome are born without a uterus, cervix, and upper vagina. They may also have underdeveloped ovaries and fallopian tubes.

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Signs & symptoms

The main symptom of MRKH syndrome is the absence of a menstrual period by age 16. Other symptoms may include lower abdominal pain, discomfort during sexual intercourse, and difficulty with urinary tract infections.

Diagnosis

The diagnosis of MRKH syndrome is usually made based on a physical examination and imaging tests, such as an ultrasound or magnetic resonance imaging (MRI) scan. Genetic testing may also be performed to confirm the diagnosis.

Treatment

Treatment for MRKH syndrome usually involves surgery to create a neovagina, which is a surgically created vagina using a tissue graft or dilators. Hormone therapy may also be used to stimulate the development of secondary sex characteristics, such as breast development. In some cases, assisted reproductive technologies, such as in vitro fertilization (IVF), may be used to achieve pregnancy.

Note

☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.

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