What is it?

Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a congenital condition in which the female reproductive system does not develop properly. Women with MRKH syndrome are born without a uterus, cervix, and upper vagina. They may also have underdeveloped ovaries and fallopian tubes.

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Additional names

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Signs & symptoms

The main symptom of MRKH syndrome is the absence of a menstrual period by age 16. Other symptoms may include lower abdominal pain, discomfort during sexual intercourse, and difficulty with urinary tract infections.


The diagnosis of MRKH syndrome is usually made based on a physical examination and imaging tests, such as an ultrasound or magnetic resonance imaging (MRI) scan. Genetic testing may also be performed to confirm the diagnosis.


Treatment for MRKH syndrome usually involves surgery to create a neovagina, which is a surgically created vagina using a tissue graft or dilators. Hormone therapy may also be used to stimulate the development of secondary sex characteristics, such as breast development. In some cases, assisted reproductive technologies, such as in vitro fertilization (IVF), may be used to achieve pregnancy.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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