What is it?

Retroperitoneal tumors are rare tumors developing in the retroperitoneum. The retroperitoneal tumors are divided into benign and malignant tumors. 70-80% of the soft-tissue tumors are malignant. Retroperitoneal sarcoma is an orphan malignant disease, which rarely occurs. There are also metastatic lesions in the retroperitoneum.
Peritoneal cancer is a rare cancer which develops in the thin layer of tissue that lines the abdomen, uterus, bladder and rectum. Primary peritoneal cancer is more common in older women, especially those who are at higher risk for developing ovarian cancer.

10 Alikes with Malignant Neoplasm of Retroperitoneum & peritoneum

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Malignant Neoplasm of Retroperitoneum & peritoneum.

Additional names

This group contains additional names:
- Cancer of Retroperitoneum & Peritoneum

Signs & symptoms

The symptoms of retroperitoneal tumors are not specific but may include abdominal swelling, early satiety and abdominal discomfort. Peritoneal cancer symptoms may include abdominal discomfort, bloating, cramps, wellings, fullness feeling, nausea, diarrhea, constipation, loss of appetite, frequent urination, unexplained weight gain or loss, abnormal vaginal bleeding, rectal bleeding and shortness of breath.


Diagnosis is based upon findings in medical history and physical examination. A CT is the first imaging investigation of choice. For peritoneal mass, other tests may include ultrasound, CA-125 blood test, lower GI series or barium enema and upper GI series. A biopsy may also be performed.


Treatment depends on the type and subtype of tumor, as wekk as the stage, grade, size and location. For retroperitoneal sarcoma, complete surgical resection is the only potential curative treatment. Radiotherapy is also sometimes a treatment option, while chemotherapy has not shown consistent evidence of a disease-free survival benefit although there may be certain situations where it is advantageous. For peritoneal cancer, surgery and chemotherapy are an option, HIPEC (hyperthermic intraperitoneal chemotherapy) could be done after surgery, by administering heated chemotherapy in metastases from appendix, colon or stomach.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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