What is it?

Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC), is a genetic condition that increases the risk of many kinds of cancer, such as colon and endometrial cancer. This condition is passed from parents to children. people diagnosed with Lynch syndrome should have careful testing to look and to early diagnose cancer tumors when they are small and hasn't spread yet.

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Additional names

This group contains additional names:
- Hereditary Nonpolyposis Colorectal Cancer (HNPCC)

Signs & symptoms

People with Lynch syndrome may experience: early age of colon cancer or endometrial cancer (before age 50), a personal history of more than one type of cancer. Tumors of the gastrointestinal tract can be manifest with bowel obstruction, blood in your stool or vomiting blood, abdominal pain, weight loss, or loss of appetite.


Diagnosis Lynch syndrome might start with a preview of your family history of cancer. Several cases of cancer in your family, especially in relatively young ages, may require further tests. Diagnostic tests may include genetic tests to detect mutations that linked to Lynch syndrome, endoscopic tests to check for polyps or gastrointestinal tumors. If cancer cells have found, they can be tested for HNPCC mutations.


There's no cure for Lynch syndrome. People with this condition should have careful testing to diagnose tumors in early stages. Sometimes more serious disease can be prevented by removing some organs like the large intestines or the uterus. Both the healthcare provider and the patient should consider the risks in either choice.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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