What is it?

Li-Fraumeni syndrome is a rare genetic disorder that increases the risk you to develop a malignant disease. People who have Li-Fraumeni syndrome have a 90% chance of developing one or more types of cancer in their lifetimes. Female with Li-Fraumeni syndrome have a nearly 100% chance of developing breast cancer in their lifetime.
The more common types of cancer seen in the population are:
- Soft tissue sarcoma - can developed in muscles, tendons fat, blood vessels, and lymph nodes.
- Osteosarcoma - a rare bone cancer. Usually affects teenagers.
- Breast cancer - almost 100% chance to develop breast cancer in lifetime for female.
- Gliomas , medulloblastoma, and choroid plexus carcinoma- forms of brain cancer.
- Neuroblastoma - a malignant tumor developed in nerves tissue.
- Adrenocortical carcinoma - this is a type of cancer that forms on people’s adrenal cortex.
Acute myeloid leukemia - a blood cancer that starts in people’s bone marrow

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