What is it?

Hypothalamic obesity is a type of obesity that occurs due to damage to the hypothalamus, which is the area of the brain responsible for controlling appetite and metabolism. It can occur due to a variety of causes, including brain tumors, brain surgery, infections, traumatic brain injury, and genetic disorders.

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Signs & symptoms

Symptoms of hypothalamic obesity can include excessive weight gain, increased appetite, and difficulty losing weight despite efforts to do so. Other symptoms can include insulin resistance, high blood pressure, and dyslipidemia (abnormal levels of cholesterol and other lipids in the blood).


Diagnosis of hypothalamic obesity involves a thorough medical history and physical examination, as well as laboratory tests to assess hormone levels and metabolic function. Imaging studies, such as magnetic resonance imaging (MRI) or computed tomography (CT) scans, may also be used to assess the hypothalamus and surrounding structures.


Treatment of hypothalamic obesity can be challenging, and may involve a combination of lifestyle modifications, medications, and surgery. Dietary interventions, such as calorie restriction and increased physical activity, are typically recommended. Medications such as liraglutide and metformin may be used to help control appetite and improve insulin resistance. In severe cases, bariatric surgery may be considered.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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