What is it?

The hypothalamus is a brain structure that regulates many body functions. Hypothalamic dysfunction refers to a condition which is characterized by damage to the hypothalamus resulting in decreased hormone release. It may be caused due to traumatic brain injury, brain infection, tumor, aneurysms, significant weight loss, brain surgery, radiation therapy or chemotherapy, multiple sclerosis or growth hormone deficiency.

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Signs & symptoms

Symptoms may include hypertension or hypotension, weight loss, weight gain, muscle loss, weakness, changes in body temperature, insomnia, frequent urination, delayed puberty and infertility.


Diagnosis is based upon findings from medical history and physical examination. Further evaluation may include blood tests and imaging tests.


Treatment may include medications to replace the lost hormones or brain injury if needed.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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