Understanding Gastric intestinal metaplasia: Causes, Symptoms, and Management

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Gastric intestinal metaplasia

by Alike Medical Team ∙ Updated on June 13, 2023

General

Gastric cancer is the third leading cause of cancer mortality and the leading cause of infection-associated cancers. Gastric intestinal metaplasia is an intermediate precancerous gastric lesion in the gastric cancer cascade. Although the risk of gastric cancer is increased in patients with gastric intestinal metaplasia, the absolute risk is modest. specific subsets of patients with gastric intestinal metaplasia may be at higher risk for progression.

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Signs & symptoms

Gastric and intestinal metaplasia usually does not cause specific symptoms and is often found incidentally in patients undergoing gastroscopy for complaints of upper abdomen pain. However, intestinal metaplasia is associated with gastric hypochloridria (lack of gastric acid), which may result with bacterial overgrowth and symptoms such as bloating, abdominal discomfort, and diarrhea.

Diagnosis

The diagnosis of gastric intestinal metaplasia may be suspected based on endoscopic findings, but it is established by histology. High-quality endoscopy examination is needed improve detection.

Treatment

In individuals with high-risk gastric intestinal metaplasia we perform surveillance gastroscopy at the three year interval

Note

☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.

National Institutes of Health ∙ World Health Organization ∙ MedlinePluse ∙ Centers for Disease Control and Prevention

☝ All information has been reviewed by certified physicians from Alike

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