What is it?

Ewing Sarcoma is a rare tumor of the bones and soft tissue around the bones such as cartilage or nerves. The typical bones for growth of the tumor are the leg and pelvis but it can occur in any bone. This condition is more common in children and adolescents, and in Europeans. The cause of Ewing sarcoma is still unknown, and it does seem to be genetic or familial. Environmental factors were not found to be linked with Ewing sarcoma.Ewing sarcoma may spread, most often to other bones and the lungs. Recently, there had been a division of Ewing sarcoma to four types of cancer:
Ewing's sarcoma of bone, Ewing's sarcoma of soft tissue, primitive neuroectodermal tumor (PNET) which may occur in both bone and soft tissue, and Askin's tumor, a PNET that occurs in the bones of the chest.

22 Alikes with Ewing Sarcoma

Learn from others
who are experiencing
Ewing Sarcoma.

Additional names

This group contains additional names:
- Adamantinoma of long bone
- Articular cartilage cancer
- Bone and cartilage cancer
- Chondrosarcoma
- Diaphyseal medullary stenosis with bone malignancy
- Extraskeletal osteosarcoma
- Osteitis deformans

Signs & symptoms

Symptoms may include pain, swelling in the affected area, fatigue, fever without a known source and weight loss.


Diagnosis is made based on the symptoms and physical examination alongside imaging tests such as an X-ray, CT, MRI, PET and bone scan. Then, a biopsy may be taken with a needle or in a surgical biopsy. The tissue may be sent for a genetic test to determine which DNA changes are present in the cells. Ewing sarcoma cells usually have changes in the EWSR1 gene.


Treatment for Ewing sarcoma often begins with chemotherapy, followed by surgery to remove the tumor. After the surgery, it is sometimes necessary to keep with chemotherapy and/or start radiation therapy.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

Learn more about our editorial process for content accuracy.

Alike Wisdom

Instantly get answers to medical questions with our AI, built from the collective wisdom of our community facing similar experiences

Thank you! Your submission has been received!

Find people who are
experiencing a similar
medical reality

100% Free