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Diffuse (eosinophilic) fasciitis
Diffuse (eosinophilic) fasciitis
by Alike Medical Team ∙ Updated on June 13, 2023
General
Eosinophilic fasciitis is a syndrome in which tissue under the skin and over the muscle, called fascia, becomes swollen, inflamed and thick. The skin on the arms, legs, neck, abdomen or feet can swell quickly. The condition is very rare. EF may look similar to scleroderma, but is not related. Unlike scleroderma, in EF, the fingers are not involved.
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Signs & symptoms
Symptoms may include: * Tenderness and swelling of the skin on the arms, legs, or sometimes the joints (most often on both sides of the body) * Arthritis * Carpal tunnel syndrome * Muscle pain * Thickened skin that looks puckered
Diagnosis
Tests that may be done include: * CBC with differential * Gamma globulins (a type of immune system protein) * Erythrocyte sedimentation rate (ESR) * MRI * Muscle biopsy * Skin biopsy (the biopsy needs to include the deep tissue of the fascia)
Treatment
Corticosteroids and other immune-suppressing medicines are used to relieve symptoms. These medicines are more effective when started early in the disease. Nonsteroidal anti-inflammatory drugs (NSAIDs) may also help reduce symptoms.
Note
☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.
National Institutes of Health ∙ World Health Organization ∙ MedlinePluse ∙ Centers for Disease Control and Prevention
☝ All information has been reviewed by certified physicians from Alike
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