Understanding Carcinoma in situ of Bladder: Causes, Symptoms, and Management

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Carcinoma in situ of Bladder

by Alike Medical Team ∙ Updated on June 13, 2023

Additional names

This group contains additional names: - Cancer in situ of urinary bladder

General

Bladder carcinoma in situ is (CIS), or Ta, or Tis bladder carcinoma, is the earliest stage of squamous cell cancer of the bladder. In this early stage, the abnormal cells are found only in the outermost layer and have not yet invaded the deeper layers of the bladder. From this stage, the disease can progress to invasive carcinoma, if left untreated. Risk factors may include smoking, radiation to the pelvis area, exposure to certain chemicals, exposure to pioglitazone medication, arsen, being male, chronic bladder infections (such as Schistosomiasis), bladder birth defects, genetics and family history.

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Signs & symptoms

Symptoms of bladder CIS may inlcude bladder irritabilty urinary frequency, urgency, pain while urinating. Rarely, hematuria, which is the presence of blood in urine, is seen.

Diagnosis

Bladder CIS is diagnosed by biopsies of the abnormal areas, detected by cystoscopy.

Treatment

Treament of bladder CIS begins with transurethral resection (TUR), biopsy with electrical (cautery) or laser thermal destruction of all visualized cancer. If there are extensive multiple superficial cancers or if the CIS was unresponsiveness to prior therapy, Radical cystectomy (complete removal of the bladder) may be done..

Note

☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.

National Institutes of Health ∙ World Health Organization ∙ MedlinePluse ∙ Centers for Disease Control and Prevention

☝ All information has been reviewed by certified physicians from Alike

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