What is it?

Amplified Musculoskeletal Pain Syndrome is a type of chronic pain syndrome that primarily affects children and adolescents. The condition is characterized by pain that is amplified or disproportionate to the level of injury or underlying medical condition. AMPS is thought to result from abnormal pain processing in the central nervous system, which leads to heightened sensitivity to pain.

14 Alikes with Amplified Musculoskeletal Pain Syndrome

Learn from others
who are experiencing
Amplified Musculoskeletal Pain Syndrome.

Signs & symptoms

The symptoms of AMPS may include widespread pain, stiffness, fatigue, and difficulty with daily activities. The pain may be described as burning, aching, or stabbing, and may be accompanied by swelling or changes in skin color or temperature. The pain may also be exacerbated by stress or anxiety.


The diagnosis of Amplified Musculoskeletal Pain Syndrome (AMPS) is typically made by a pediatric rheumatologist or pain specialist. The diagnostic process involves a thorough medical history and physical examination to assess the child's symptoms and rule out other underlying medical conditions that could be causing the pain.

Diagnostic tests may also be performed to help confirm the diagnosis and rule out other conditions. These tests may include blood tests to check for signs of inflammation or infection, imaging studies such as X-rays, MRI or ultrasound to evaluate the joints and surrounding tissues, and nerve conduction studies to evaluate nerve function.


The treatment of Amplified Musculoskeletal Pain Syndrome (AMPS) typically involves a multidisciplinary approach that includes a combination of medication, physical therapy, psychological counseling, and relaxation techniques.
Medications that may be used to treat AMPS include non-steroidal anti-inflammatory drugs (NSAIDs), low-dose antidepressants, and anticonvulsants. These medications can help reduce pain and improve sleep and mood.
Physical therapy can also be helpful in treating AMPS. Physical therapists can develop a customized exercise program to help improve flexibility, strength, and endurance, and reduce pain and stiffness. Other physical therapy techniques that may be used to treat AMPS include massage therapy, heat therapy, and transcutaneous electrical nerve stimulation (TENS).
Psychological counseling can also be an important part of the treatment of AMPS. A mental health professional can help the child and family learn coping strategies and relaxation techniques to manage stress and anxiety, which can worsen the pain symptoms.
Other complementary therapies that may be used to treat AMPS include biofeedback, acupuncture, and hypnotherapy.
The goal of treatment is to reduce pain, improve function, and help the child return to their normal activities. The treatment plan will be tailored to the individual needs of the child and may involve a combination of these therapies.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

Learn more about our editorial process for content accuracy.

Alike Wisdom

Instantly get answers to medical questions with our AI, built from the collective wisdom of our community facing similar experiences

Thank you! Your submission has been received!

Find people who are
experiencing a similar
medical reality

100% Free