What is it?

Perforation of a duodenal ulcer causes gastric and duodenal contents to accumulate in the peritoneal cavity, with a resulting initial chemical peritonitis.
Leakage of gastroduodenal contents can also lead to bacterial infection of the peritoneal cavity, due to bacteria and undigested food in the peritoneal cavity.

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Acute duodenal ulcer with perforation.

Signs & symptoms

Sudden onset of epigastric pain, Generalized pain, occasionally, in the right lower quadrant, Hypotension, High fever in case of an infection or inflammation in peritoneal cavity.


In physical examination, the patient shows signs of epigastric pain and generalized abdominal pain, and abdomen rigidity.
Chest X Ray free air can be seen in about 80% of cases.
Gastroduodenogram will show the leak from the duodenum or its sealing.


The traditional management of a perforated duodenal ulcer is a laparoscopic surgery.
In approximately 40–50% of cases the ulcer self-seals - without any specific treatment.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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