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General
Acromegaly refers to a condition which is characterized by overproduction of growth hormone during adulthood. In adulthood, excess growth hormone does not lead to getting taller but rather to increased size in hands, face and feet. The change spreads over a long period of time so it is sometimes hard to notice. It is caused due to pituitary tumors (cancerous and non-cancerous) or non pituitary tumors which release GH but it is quite rare.
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Signs & symptoms
Symptoms may include enlarged hand and feet, changes in the face shape, enlarges nose, wider space between the teeth, thickened skin, excessive sweat, skin tags, fatigue, snoring, vision problems, headaches, erectile dysfunction, irregular menstrual cycle in women, and decreased libido.
Diagnosis
Diagnosis is based upon findings from medical history and physical examination. Further evaluation may include IGF-1 measurement in the morning after fasting the night, growth hormone suppression test and imaging of the brain.
Treatment
Treatment usually includes surgery with or without radiation to remove the tumor and medications such as somatostatin analogue to inhibit GH production, and dopamine agonist to help lower GH and IGF-1 levels.
Note
☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.
National Institutes of Health ∙ World Health Organization ∙ MedlinePluse ∙ Centers for Disease Control and Prevention
☝ All information has been reviewed by certified physicians from Alike
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