Any concrete treatment suggestions for CFS? Medications or therapies that have provided relief for your fatigue? I’m at my wit’s end. Doctors don’t really seem to know what to do with me, other than vague suggestions to pace myself. Thanks in advance.


Myalgic encephalomyelitis/ Chronic fatigue syndrome (ME/CFS)



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  • KeyRed


    For me, Wellbutrin has made my fatigue go from a 10 to a low 9 (sometimes 8). It was originally prescribed for dopamine but it's worked for my me/cfs. I was unaware of this change until last year when I attempted to go off of them and it jumped back up to 10. You should ask about it.

  • meatball


    Pacing is honestly the best advice. Whenever you overexert yourself mentally, physically and/or emotionally, you'll go into a post exertional malaise (PEM) crash. If you avoid overexertion, your baseline level of fatigue will lessen! This is way easier said than done. You'll probably have to cut your activity level wayyy back (I was a competitive powerlifter, training 8hrs/week, and I had to drop down to 0 and be mostly bedbound). However, I've been pacing very carefully and was able to start doing some light movements without crashing. Just know that if you overexert and crash, your baseline fatigue will worsen. Staying on the safe side and being conservative with movement, studying/working and any stressful environments is your best bet!

  • princessbun


    When I was on antibiotics I felt amazing (why? I dont know.) I was even able to exercise. I tried amoxicillin, as well as a natural one called candibactin-AR. I originally used them to treat SIBO caused by POTS. Things went back to normal and I'm exhausted again while not on medicine. Right now I am looking into low dose naltrexone, IV ozone therapy, and stem cell therapy. There is real evidence for these treatments, they are just super pricey.

  • Leahkes


    I have really had to learn to be my own advocate since my diagnosis. You’re so right. No one knows what to do with us. My doctors keep telling me “you have to find what works for you,” but over the years, I had tried everything. I finally went off all my meds last year and I only take Kratom. It’s not for everyone, but my experience has been overwhelmingly positive. If you’re in the US, it’s worth exploring. I wish you all the best as you continue to navigate life with this terrible, terrible disease that is so easy for others to dismiss.

  • Raze


    Check out a doctor by the name of Dr. Jacob Teitlebaum. (Not cheap but look at all you’ve spent already) He is a case of “I wish I had known about him sooner.” He had Chronic Fatigue during college at medical school. So he knows what we are going through. He helped me dramatically but not 100%. What eventually helped me was TMS = Transcranial Magnetic Stimulation. Google Success TMS. It is an FDA approved treatment that helps with anxiety and depression. It basically wakes up the epinephrine, serotonin and dopamine that has gone dormant in your brain to try and protect itself. The brain fog and no motivation went away after this treatment. My energy still remains impacted but that is more mitochondria. Avoid sugars!! Exercise as able. Stay motivated even when it seems impossible. I look forward to sharing experiences so we can help each other become the people we know we can be !! 🙏

☝ This content is generated by our users and it is not a substitute for professional medical advice. Please consult with your physician before making any medical decision

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