I took Zoloft for seven years. It worked fantastically for years with adjustments, but I reached the top dosage they were willing to prescribe. After many failures in trying to add a booster, I was eventually weaned off Zoloft and placed on Paxil. I was incredibly nervous, as I'm fearful of change, but it was the best thing for me. I haven't felt this good since I was first placed on Zoloft.

I know they have the same function but maybe ask your doctor if you can switch to Lexapro? Your body might have a tolerance to Sertraline, so maybe Escalitopram might work. Just a possibility.

I take 150mg of Zoloft so you have some room to increase your dosage. If 100mg was a big jump, I'd give 75mg a chance. It might just be enough to make a difference for you. I know it's helped me.

I take 200mg . Which is max. I would try upping your dosage before adding another meds

I've taken Zoloft for 7 or 8 years and if I felt like it wasn't working, I just asked for a higher dose. You're very unlikely to develop serotonin syndrome if you're not taking anything else that affects serotonin production. Your doctor can work with you to determine what the next step is for your treatment, if you feel like something needs to change, tell them!

My best advice is to either increase dosage, switch drugs (there are many different antidepressants), or add another drug. I used to be on Zoloft w/ Wellbutrin but now after years of trial and error I'm on Prozac and Wellbutrin which seems to be keeping me pretty level.

I had an awful experience with Zoloft. It increased my depression 10 fold. I had to be hospitalized for 3 weeks while they weaned me off of it and switched me to Lexapro.