Has anyone taken tramadol and Effexor? My psychiatrist has been trying to get me on SNRI or mood stabilizer but I typically have bad reactions. Tramadol works great for me but only gives me a few hours of relief to be functional. I was looking up that Effexor is similar (minus mu opioid activity) to tramadol and can help with pain and mood. Wondering if it’d be worth it to try Effexor since my tramadol dose is low to help get pain and mood to a manageable level. Does anyone have experience with this? Or further suggestions? I’ve tried a lot of other meds for anxiety, depression, pain, nerve issues, bipolar/stabilizers with no success.