I noticed you tagged bipolar but listed major depression in your post. Your diagnosis does matter here because a lot of people with bipolar have bad reactions to antidepressants. Mood stabilizers work better. Latuda is an option for sure, but if you have bipolar I would look at anticonvulsants first since they tend to have fewer negative side effects than antipsychotics. I personally take Lamictal and have had a wonderful experience. I don’t get side effects at all (except for a rash I had for a few days when I first started taking the med). This is significant because I’m someone that literally gets every rare side effect ever. I like Lamictal because it helps with the depression elements of bipolar which is the bigger concern for me. I’ve tried Latuda before and it personally made me much more suicidal. I’ve also tried Abilify as someone suggested above and got so nauseous that I could barely eat one meal a day. Most people don’t have that many side effects on those meds and they are safe an everything. I just have a weird med experience lol. But still in general anticonvulsants are better for your body long term than antipsychotics. Ultimately what matters is if the med helps your mental health, but I’d try things that are gentler on your body first:) Hopefully this makes sense. I’m trying this right before bed.