Sertraline Tolerance

Yes, I've had that happen to me with several medications. Don't let it get out of hand. For me, it eventually got so bad I ended up in the hospital 3 times. I'm finally doing better. Eventually I settled into a treatment routine of ECT, weekly Spravato treatments, weekly counseling, daily Lexapro medicine, and prescription strength Vitamin D.

i’m at 200 of zoloft, i’ve taken it for over 5 years. Recently my doctor added lithium, which I was skeptical about because of the risks and the fact that it’s used for bipolar, which I am not, but it’s made a big difference honestly. Im only on 600mg of lithium along with the 200mg of zoloft but the effects are really great for me!!

@melloyello789 what did they add to your sertraline? I’m going to the doc today to talk meds.

I went all the way to 250 and it just didn’t do any good, but increasing it might help for sure. They might also need to pair something with it because that’s what it took to help me.

My psychiatrist has upped my dose and have see quite an improvement!

it's incredibly common to build up tolerances to psych meds after a few years!! upping your dose might help but sometimes all you can do is switch to something else for a few years so that tolerance goes away. it's an unfortunate reality of taking these kinds of medications, and totally normal!