I really didn't have any problems taking it, however, everyone is different. Express your concerns with your doctor and or your pharmacist.

I’ve been on methotrexate since getting COVID in April 2020 which led to pericarditis and now RA. I really haven’t had any problems with methotrexate. Although I was taking 2.5 mg 8 tablets once a week but they just reduced it to 7 pills because my blood work came back a little off on my kidneys

Methotrexate was the first drug prescribed to me, when I developed RA as a child. I had no side effects. As someone who has been med free and medicated, life is barely manageable during a flare. Not taking medication, does more physical and emotional harm than any prescribed drug.

Since the methotrexate alone wasn't relieving my pain entirely they put me on a low dose of prednisone along with it. Which helps very much but it also wipes out your immune system so I got sick 4 days ago. None I know is sick so musta just picked it up somewhere. So that's a downside. Spent mother's day home alone sick.

I have severe RA and was also very low on my vitamin D. I started taking 6,000 IU of the vitamin D a day and my numbers are 👌🏼 and my doctor also recommended Folic Acid and I take biotin to get my hair strong. I do get really tired in the days I take methotrexate but I just listen to my body and take it easy in any way I can. My best advice in this regards is to be gentle with yourself and if you need to take it slow for a day, it’s okay. Your body is healing/ being treated from/ for a lot of internal distress. Hope this helped a little bit!