Long-term Treatment-Resistant Depression

Yep. I have been on all the anti depressants out there and my depression and anxiety is still constant and they are both alive and well. Nothing I have tried works.

My neurologist speaks highly of ketamine treatment. I'm considering if my switch from Cymbalta to Paxil is ineffective. I had to wean off Cymbalta in 4 wks (after being on it for at least 8 yrs) for allergy testing by my ENT. Something about the medication would interfere with my skin allergy results. I got back on it immediately and my anxiety isn't controlled anymore and when I began feeling sad, I saw a psychiatrist. I was told that sometimes stopping an anti-depressant, then restarting it can cause it to not work for me anymore.

Me to no energy and I just don't care about anything anymore, I just lay in bed as time passes by

I feel like I cycle through stages of depression. It just shifts from one thing to another or drifts into numbness and I can't give a specific reason for the feeling, or non feeling... I'm so tired of medication and feeling that it's just a bandaid.

👍I have no interest and energy

This is how I feel too. I just have no energy or interest. You are not alone.

I do, no matter what I try ,what medication I'm given nothing helps. I don't think I'll ever be me again

😥I am retired. I have CPTSD but things got real bad when my mom died 2 days before Thanksgiving in 2015. My life has been crazed ever since. I just sit. I don't clean, rarely cook, and have a husband of 42 years. He isn't well, but does all he can to do what HAS to be done. I can't stand what I have become. I don't call friends, I can Stare into the room for hours as the day slips away. I don't want to die. But, I can't seem to live- really participate in life. Almost losing my husband during Covid ( he had 3 strokes in 4 months) did not help. I want to be better, but I am not who I was. I can't seem to get myself " back".

I do