I'm taking 150mg 2x daily for my epilepsy. I have had the same issues, and started taking vitamin b6 once a day and have noticed a tremendous difference! It's helped with my motivation and ability to stay awake and push through those low times. I suggest staying in touch with your doctor and letting them know. Maybe it's not the right medication for you. Hope this helps!

I take 250mg for epilepsy. I'm suppose to take it twice a day but when I do I have bad nightmares so I take mine once and I prefer taking it in the evening around dinner time or after dinner. I don't have nightmares with just once and I'm not groggy during the day.

I used to take it at night too because I felt like it dulled me if I took it in the morning