Genetic Testing for MM Inquiry

There is currently a study with a test happening to learn about genetics and MM. It's called "The Promise Study" and it's for those with a first degree relative with multiple myeloma or another blood cancer. Here's the link for more information: https://www.enroll.promisestudy.org

When you get a bone marrow biopsy they look for changes to your genes. Translocations, additions and deletions.

Thanks for sharing your story.I must say you're incredibly strong on the inside for reaching out for support. I went through this stage and I know exactly how it feels like.Everyone’s body has a specific way of reacting to MM, I can’t really tell how your body will respond but I can tell you how mine went and prolly this might help you. I was diagnosed in September 2019 and I started chemo shortly after. I was put on Elotuzumab , lenalidomide, and dexamethasone over a period of 4 weeks cycle which was repeated. I did 6 cycles over a period of 6months. I finished in this plan in 2020 and I have complete remission. I then had 15 days of radiotherapy in my right pelvis which ended in October. In late November I was admitted to the hospital for radiation colitis, part of my descending colon was resectioned. I lost my appetite, my taste changed and I lost weight. I did mostly soups and drinks recommended by my medical team. I think now my weight is beginning to stabilize. I didn’t get any infections because I made sure I kept good hygiene.I was on oral and slow-release morphine for the pains. I also received infusions to strengthen my bones every 4 weeks which will run for another year, but I still feel weak most of the time. I was only able to exercise for a few minutes at a time in a day. I won’t be going in for a stem cell transplant , I don’t think I’ll need it at this time since I am currently in complete remission. I hope this helps, please feel free to ask me anything.

I think there’s no definite answer on this for sure. In my case, I did follow-ups and constant monitoring with my doctor. I also tied it up with lifestyle changes..and I have not been knocked out of remission for the past 4 years. Talk to your doctor and see how he goes. cheers !

I've heard of a useful genetic test that can help identify abnormalities in your chromosomes. It is called FISH test and can really help with prognostic implications and treatment decisions. Additionally, there are other tests which are not genetic but equally useful. One such test called IFX is quite sensitive and can tell if there are any signs of monoclonal protein in your blood. And if the results are clear of monoclonal protein, then there's a 98% chance that you don't have multiple myeloma. Let me know if this helps!

I don't think everyone needs to do this testing, I didn't or at least I'm not aware of its results, I'd recommend discussing it with your doctor to see if it's appropriate for you.

Hey there! yeah, there are genetic tests available for mm that can help identify genetic mutations or abnormalities. they sometimes help with determining the prognosis and treatment options. Hope this helps! 💡