Frequent Headaches and Ineffective Medication: Seeking Advice

One possible reason could be that the individual has developed a tolerance to the medication, as seen in the case where Excedrin stopped being effective after being taken frequently for a long period of time. Another possibility is that the headaches are caused by an underlying condition that isn't being addressed by the current medication. For example, one person mentioned that their headache might be caused by undiagnosed POTS (Postural Orthostatic Tachycardia Syndrome). It's also possible that the medication being used simply isn't strong enough to manage the severity of the headaches.