Looking for experiences with duloxetine for fibro/ME

My doctor & I moved me to duloxetine (Cymbalta) just under a month ago for suspected fibro/ME. No negative side effects so far (phew!) but I haven't noticed much relief either. For those who've taken it a bit longed and did see improvement, about how long did it take? And, when you noticed positive change, what stood out the most?

Your answer

chickybones

2y ago

I take gabapentin at night. It helps a little

dailydose

2y ago

For the pain, personally didn’t make a huge difference but it has helped me mentally. Lyrica has helped me a lot more with fibromyalgia pain than duloxetine has

sleepynoodle

2y ago

It took me about 8 weeks to notice any difference at all, hang in there 🤗

pianolover314

2y ago

I actually haven't had much effect with it either except I think mentally. Maybe not even mentally. Been taking it for a year and a half. I was on fluoxetine/Prozac, my rheum suggested cymbalta instead, then I got a psychiatrist couple months later and he said the two meds work different parts of the brain so u can take both

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