Antipsychotics for Treatment Resistant Depression: Experiences?

i have been on abilify, and stopped after around 5 days due to the side effects. originally, it was to stabilize my mood, but i have really bad depression and after the first day which was very manic it made me have a very unpleasant depressive episode that lasted four days and was unlike anything i had really experienced before. i decided to stop not only because of this but because of the frequent cholesterol checks in which i had to get my blood drawn (my anxiety is really bad when i get my blood drawn!). i don’t believe i’ve seen an experience similar to mine but it just didn’t work out for me. additionally, i was on my antidepressants (cymbalta) the whole time while trialing this medication. hope this helps!<3

When my antidepressant stopped working my doctor continued me on it and added Abilify and that seemed to help

Lamotrigine has worked really well for me. I’ve taken it for a while. It’s originally for seizures but it helps with depression and is a mood stabilizer. It really helps my bouts of depression not get so low.

I was prescribed it in the past for sleep. But I ended up sleeping a lot and still being exhausted. It did not like it. I do take 2 mood stabilizers that seem to help though.

I’ve been on it for sleep, it did help I had to stop. Made me so groggy. I’d walk down the street and ppl would think I’m drunk. That’s my experience I hope it helps you!

Hi! So I was on Seroquel for about a month and all it did was knock me out. Like, I was asleep within 15 minutes of taking it and I hated how it made me feel. But! That’s just my story and I was in a really dark place so I needed to be knocked out

Hello to my highest match on here so far! Seroquel made me gain a TON of weight and didn't do anything for my depression. But, wellbutrin did nothing for my depression either so you likely respond to medications differently than I do. I started a very new type of therapy and I actually went an entire year (even winter) depression-free for the first time since early middle school.

I have recently switched to an antipsychotic and it seems to be helping