Understanding Recurrent pregnancy loss: Causes, Symptoms, and Management

What is it?

Recurrent pregnancy loss is defined as having two or more miscarriages. Most pregnancy losses result from chromosomal or genetic abnormalities. Other causes for pregnancy loss may include uterine abnormalities, hormone abnormalities such as thyroid disease and diabetes, and abnormalities in the mother’s blood clotting. Women who have had recurrent pregnancy loss will go through testing to find the underlying cause. In most cases, no abnormality will be found and the change for a successful pregnancy is high.

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Additional names

This group contains additional names:
- miscarriage
- recurrent miscarriage

Diagnosis

Diagnosis is based upon findings from medical history and physical examination. Further evaluation may include genetic testing for both partners, imaging tests of the uterus, blood tests for hormone functions, Antiphospholipid antibodies, anticardiolipin antibody and lupus anticoagulant, and blood clotting factors.

Treatment

Treatment depends on the underlying cause and may include prenatal genetic studies with either chorionic villus sampling or amniocentesis. In vitro fertilization with preimplantation genetic diagnosis (PGD) can also be done. Surgery may be done for some of the uterine abnormalities. For women with hypercoagulable conditions, medications to reduce blood clot formation may be given, and for hormonal imbalance specific medications may be prescribed.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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Source of Information - We analyze big data of more than 23 million patients de-identified medical records from the following sources:

National Institution of Health ∙ World Health Organization ∙ University of Illinois hospital