What is it?

-Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu) is an inherited disorder, causing abnormal connection between arteries and veins, called arteriovenous malformations (AVMs). It is common in the nose, lungs, brain and liver. These malformations can grow bigger with time, and they are at greater risk to bleed or rupture, which can lead to serious complications. The most common characteristic of the disease is frequent nosebleeds.

-Nevus is a mole, a non neoplastic nevus is a benign mole. Moles are small brown, tan or pink spots, usually appearing between ages 10-40, but it could also grow later in life due to sun exposure. There are different types of nevi.

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Additional names

This group contains additional names:
- Capillaritis
- Conjunctival telangiectasis
- Dilated capillaries
- Familial pigmented purpuric eruption
- Hereditary benign telangiectasia
- Increased blood vessel permeability
- Increased capillary permeability
- Increased capillary resistance
- Secondary telangiectasia
- Solar telangiectasia
- Telangiectasia

Signs & symptoms

Hereditary hemorrhagic telangiectasia symptoms may include nosebleeds, tiny red spots on the lips, face, fingertips, tongue and mouth, iron deficiency anemia, shortness of breath, headaches and seizures.


-Diagnosis of hereditary hemorrhagic telangiectasia is based upon findings in medical and family history and physical examination. A definitive diagnosis is made by genetic testing. To look for AVM’s- US, MRI, and a CT scan may be done.
-Nevi diagnosis is done by physical examination done by the dermatologist with a special lamp. A skin biopsy can be taken from the mole, to rule out skin cancer.


- Hereditary hemorrhagic telangiectasia treatment is with hormone related drugs, drugs that block vessel growth or drugs that slow the disintegration of clots. To treat malformations, there are several surgical options, depending on the location. Skin grafts, ablation, embolizations, removal and radiotherapy are some of the options.
- Most nevi do not require any treatment. Sometimes a nevus can be removed, if it is suspected to be cancerous, or has the chance of becoming one. Also, a nevus can be removed if it interferes the patient aesthetically.

☝️ This is not a substitute for professional medical advice. Please consult with your physician before making any medical decision.

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