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Primary hypercoagulable state
by Alike Medical Teams ∙ Updated on June 13, 2023
This group contains additional names: - Factor 5 Leiden mutation
Factor V Leiden is one of the clotting factors in our blood. Mutation in one of the factor’s genes may cause hypercoagulability, causing clots mainly in the lungs and the legs, although most people will never develop blood clots. Women who have these mutations may develop blood clots under estrogen therapy or during pregnancy.
178 people with Primary hypercoagulable state

factor V Leiden mutation symptoms may include deep vein thrombosis (pain, swelling, redness and warmth) due to blood clot in the leg. This blood clot may travel through the bloodstream to the lungs and cause shortness of breath, chest pain, cough and rapid heartbeat- this could be life threatening.
Diagnosis is based upon findings from medical history, family history and physical examination. Further evaluation may include a blood test.
Treatment may include blood thinners for those who experienced blood clots, leg wraps, and compression stockings.
☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.
National Institutes of Health ∙ World Health Organization ∙ MedlinePluse ∙ Centers for Disease Control and Prevention
☝ All information has been reviewed by certified physicians from Alike
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Several individuals with **Factor V Leiden mutation** have reported experiencing reoccurring miscarriages. Some of them have managed to have successful pregnancies, but the experiences vary widely. One individual mentioned the use of blood thinners during pregnancy as a precautionary measure. Another person suggested getting a genetics test done. However, it's important to consult with a healthcare professional for personalized advice.
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